Team

 


David Quigley, PhD
David Quigley has been studying cancer genetics using bioinformatics since 2006. David received his undergraduate degree in Computer Science from Carleton College and worked as a software developer in industry for five years before complating a Masters degree in Biomedical Informatics at Columbia University. He worked for nine years as a staff scientist in the lab of Allan Balmain at UCSF and completed his PhD in Genetics with Annelise Børresen-Dale at the University of Oslo in 2014. He was appointed an Assistant Adjunct Professor in Epidemiology & Biostatistics while working with Alan Ashworth and Felix Feng in 2015. He then joined the faculty of the UCSF Department of Urology in 2020 as an Assistant Professor in Residence and was appointed the Felix Feng Endowed Professor in 2025.

Lab Members


Thaidy Moreno-Rodriguez, PhD
Thaidy Moreno-Rodriguez received her Ph.D. in Molecular Biology and Biomedicine from the Universidad de Cantabria in Spain. Her research interests are centered around how tumors develop resistance to targeted therapy in prostate cancer. Outside of the lab, she enjoys cooking, running, playing volleyball and tennis, and exploring California.

Meng Zhang, MS, PhD
Meng Zhang (co-mentored with Dr. Felix Feng) completed her PhD in Cell Biology at Yale University and an MS in Computer Science at Stanford University. She is interested in understanding the RNA biology of aggressive prostate cancer. She enjoys visiting science museums and spending time with her family.
Taopeng (Tony) Wang
Tapoeng (Tony) Wang, PhD
Taopeng (Tony) Wang completed his PhD at the Garvan Institute of Medical Research and the University of New South Wales, where he focused on evaluating, refining, and applying novel single-cell and spatial transcriptomic technologies for breast cancer research. His research aimed to characterize transcriptomic signatures and dissect upstream gene regulatory networks in cancer cells to better understand their phenotypic plasticity and identify potential therapeutic targets. Outside the lab, he enjoys watching basketball and immersing himself in the world of video games.
Jace Webster photo
Jace Webster, PhD
Jace Webster received his PhD in Human and Statistical Genetics while studying at Washington University in Saint Louis. He is broadly interested in both the creation and application of bioinformatic methods to precision oncology, with specific interests in the detection and interpretation of structural variants. Outside the lab, he enjoys reading, playing soccer, and exploring open-source software.
Siddharth Mahesh
Siddharth Mahesh
Siddharth Mahesh received his undergraduate degree in Computer Science and Computational Biology at the University of Pittsburgh. He became interested in cancer genomics while working in Paul Boutros’ lab. He is currently a graduate student in the Biological and Medical Informatics program at UCSF, focusing on applying deep learning to better understand therapeutic resistance in prostate cancer. In his free time, he loves playing sports and rooting for the Green Bay Packers.

Raunak Shrestha, PhD
Raunak Shrestha (co-mentored with Dr. Felix Feng) completed his Ph.D. in Bioinformatics at the University of British Columbia and Vancouver Prostate Centre. His current research is focused on how the chromatin state and structure affects prostate cancer progression and therapeutic resistance.

Rensheng Wan, Ph.D.
Rensheng Wan (co-mentored with Dr. Felix Feng) completed her PhD in Human Genetics at Hannover Medical School, Germany. Currently she focuses on the application of epigenetic modification changes in liquid biopsy in prostate cancer. In her free time, she likes to travel, watch shows, and go hiking!

Xiaolin Zhu, MD Ph.D.
Xiaolin Zhu (co-mentored with Dr. Felix Feng) completed medical school in Shanghai and subsequently a PhD in human genetics and genomics with David Goldstein at Duke and then Columbia University. Motivated to become a physician-scientist to advance precision medicine, he went back for clinical training and completed an internal medicine residency at UT Southwestern and is now a medical oncology fellow at UCSF. He is interested in translational genomics and human genetics of genitourinary malignancies, particularly prostate cancer. In his free time, he enjoys exploring new places, reading nonfiction, watching movies, and spotting interesting music on Spotify.

Nicholas Lillis
Nicholas Lillis received his B.A. in Biochemistry and Theoretical Mathematics from Columbia University in New York. He is interested in Machine Learning applications to genomic analysis. Before coming to UCSF, he was on a musical tour of Europe with the Columbia Kingsmen. In his spare time, he enjoys running and surfing!

William Jarrard
William Jarrard received his B.A. in Systems Engineering and his M.A. in Data Science from the University of Virginia.

Yuxin Yang
Yuxin Yang received her B.S. in Biomedical Engineering and M.S. in Biochemistry and Molecular Medicine from the University of Southern California. She is interested in studying the molecular mechanisms driving the development of lethal cancers, utilizing high-throughput sequencing data. Outside the lab, Yuxin enjoys reading, hiking, and drumming.
Aish Subramanian photo
Aish Subramanian
Since graduating from Scripps College, Aish has been dedicated to precision cancer research at UCSF. She began as a SRA in the McDonald lab, investigating the impact of immunotherapy on pancreatic neuroendocrine tumors, and then transitioned to working as a CRC role, coordinating Phase 1b-3 trials in genitourinary cancers. Currently, in the Quigley lab, Aish focuses on integrating genomic and clinical data to enhance the understanding of prostate cancer progression and treatment responses, with a special interest on developing liquid biopsy biomarkers for personalized medicine. Aish hopes to one day continue this work as a physician-scientist.

Lab Alumni

Arian Lundberg, PhD: Now an Assistant Professor at the KTH Royal Institute of Technology

Martin Sjöström, MD PhD: Now a resident and group leader at Lund University in Sweden